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[C] Change your diet, extend your life | Dr. Morgan Levine [FULL]

LET'S SHADOW DR. MORGAN LEVINE IN FULL!

Do / certain diets / tend to correlate / with certain outcomes? // There are really / three components / of diet / that seem to be impacting aging: // So the first is / how much we eat, / the second / is what we eat, / and the third is / when we eat. // So in terms of / how much we eat, / a lot of science went into this idea / of ​​caloric restriction. // Caloric restriction / isn't / starvation. // It's usually / just about a 20% reduction / in the overall calorie intake. // In a lot of different / animal models, / so / anything from / a worm, / fly, / mouse, / people have seen / that / when animals are caloric restricted, / they tend to live longer. // When trying to figure out if / something like / caloric restriction / is actually beneficial / to the aging process / in terms of slowing aging, / one caveat / is that / humans today / are not at baseline; // we're actually / more prone / to overeating. // So some researchers / have figured out / that it / might not be / the caloric restriction / that's actually / the beneficial thing. / So // even if / you can't / restrict / your calories, / just / moving away / from overeating / is probably gonna have a beneficial effect / for most people. // The other thing / that's been studied / is this / concept of / what we eat. // A lot of / research has gone into / whether things / like a plant-based diet / are actually / beneficial / to aging / and longevity. // And there seems to be / some evidence / that eating less / animal products, / more fruits / and veggies, / more whole foods / is gonna be / better overall; // and / also / minimizing things / like / refined sugars, / and / the things / that we know / are bad / for our health. // The third // comes down / to / when we eat, / and this is / really / a / new field / in aging / and longevity science. // So // again, / most people / aren't gonna be able to / calorically restrict, / but what / scientists found / is actually / fasting can mimic / some of the benefits / that we've seen with caloric restriction. // So if / people can / perhaps / minimize their eating / to a small window, // we think / that this can actually / recapitulate / a lot of the benefits / that we're seeing / in the / caloric restriction studies. // The idea/ of ​​why / things like / caloric restriction / or fasting / might actually / improve / our aging process / is because / we think / this evokes / this idea of / 'hormesis' / in our bodies. // What hormesis / refers to / is a mild stressor / that actually / makes our bodies more resilient / and robust / to stress over time. // So having / these short-term / mild stressors, / whether it be fasting / or whether it be / a small / caloric deficit, / actually makes our bodies / more resilient against / a lot of the changes we see / that increase with aging. //

LET'S UNDERSTAND!

ES_LET'SUNDERSTAND_BANNER

  1. What are the three components of diet that seem to impact aging?

  2. How does fasting relate to the benefits of caloric restriction?

  3. What is hormesis, and how does it relate to aging?

  4. What's your concept of diet, and how does it impact aging?

  5. What is the speaker's purpose of this speech?